By Karen Blum
Using a loading dose of vancomycin in patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia may not alter their clinical outcomes, a new study suggests.
In a retrospective chart review of 359 patients with MRSA bacteremia, of whom 239 received a vancomycin loading dose of at least 20 mg/kg, researchers with ChristianaCare in Newark, Del., found no significant differences in clinical failure whether or not patients received the loading dose. Clinical failure was