MARCH 24, 2022

CDI Risk Increases With 5-ASA in Pediatric IBD Patients

By David Wild

Originally published by our sister publication, Gastroenterology & Endoscopy News

The use of 5-aminosalicylic acid significantly increases the risk for Clostridioides difficile infection in pediatric patients with inflammatory bowel disease, according to a new meta-analysis.

There is scant literature and conflicting findings on CDI risk factors in the pediatric IBD population according to the investigators. For example, antibiotic use in pediatric patients has shown mixed