By Marie Rosenthal, MS
The novel COVID-19 treatment, ensitrelvir, shows both clinical symptom improvement and an antiviral effect in a predominantly vaccinated population regardless of risk factors (JAMA Netw Open 2024 Feb 9. doi:10.1001/jamanetworkopen.2023.54991.
Researchers conducted the pivotal double-blind, randomized, placebo-controlled, phase 2/3 study (SCORPIO-SR) in 1,821 patients with mild to moderate COVID-19 who were randomly selected for treatment with once-daily ensitrelvir (375 mg