MAY 30, 2025

MAD-ID 2025

Pemivibart Appears to Prevent COVID-19 Infection in CLL

By Gina Shaw

The monoclonal antibody pemivibart (Pemgarda, Invivyd) is well tolerated and appears effective in preventing symptomatic COVID-19 infection among patients with chronic lymphocytic leukemia (CLL), who can be severely immunocompromised, according to a study reported at MAD-ID 2025, in Orlando, Fla. (abstract 96E).

Authorized by the FDA under an emergency use authorization, pemivibart is indicated for certain patients with medical conditions or receiving immunosuppressive treatments