MAY 14, 2025

PCR-Based Diagnostics Can Aid in Better Management of Complicated UTIs

By Ethan Covey

The use of polymerase chain reaction (PCR)-guided therapy can significantly enhance the detection and management of complicated urinary tract infections (cUTIs), according to the results from a randomized clinical trial that have been released in three recent publications.

While culture and sensitivity (C&S) testing remains the current standard diagnostic approach, it suffers from longer turnaround times that may delay initiation of treatment. PCR-based diagnostics, on the