JANUARY 13, 2025

FDA Requires GBS Warning for RSV Vaccines

By Marie Rosenthal, MS

The FDA required and approved safety labeling changes to the prescribing information for respiratory syncytial virus (RSV) vaccines to include a warning about the risk for Guillain-Barré syndrome (GBS) after vaccination.

The labeling will apply to both RSVPreF (Abrysvo, Pfizer) and RSVPreF3+AS01 (Arexvy, GSK). The U.S. prescribing information (USPI) for each vaccine has been revised to include the same language in the Warnings and Precautions section—that