AUGUST 19, 2024

Shortened Protocol Can Prevent Infection in Recipients of HCV+ Organs

Early adopters say shortened regimen with DAAs and ezetimibe should be standard of care


Originally published by our sister publication Gastroenterology & Endoscopy News

By Kaitlin Sullivan

A shortened antiviral protocol adding the dyslipidemic agent ezetimibe can prevent infection in solid-organ recipients who receive hepatitis C virus–positive organs, according to new research presented at The Liver Meeting 2023.

The regimen, dubbed the “Toronto Protocol,” uses the current standard-of-care treatment glecaprevir-pibrentasvir (Mavyret, AbbVie) but cuts the course