DECEMBER 17, 2021

Decreased Microbiome Diversity After HCT Associated With GVHD, Mortality

By Kate O’Rourke

Originally published by our sister publication, Clinical Oncology News

A prospective analysis confirms earlier retrospective work showing there is an association between microbiome diversity and survival outcomes in patients with hematologic cancer undergoing allogeneic hematopoietic cell transplantation (HCT). 

Previous studies suggested that decreased microbial diversity in the gastrointestinal microbiome, potentially due to chemotherapeutic and antibiotic exposure,