MARCH 27, 2023

Resistance Concerns Cloud Fluoroquinolone Prophylaxis for Neutropenia

By Landon Gray

With concerns about resistance and increased potential for poor outcomes, the benefit of fluoroquinolone prophylaxis for neutropenia has been in question for some time.

Pros and cons were discussed in a recent debate hosted by Connect with the University of Pittsburgh Medical Center and Michigan Medicine and MAD-ID (Making a Difference in Infectious Diseases).

In the early era of chemotherapy, infections—primarily those with gram-negative organisms—were responsible for