FEBRUARY 28, 2025

The Cutting Edge of Respiratory Diagnostics: An Ever-Evolving Laboratory Arsenal

Jonathan Schmitz, MD, PhD, D(ABMM)

In several past articles in this publication, I have reviewed the profound changes in recent years in the laboratory diagnosis of respiratory infections.1-3 These advances have been driven largely by nucleic acid amplification technology, both the underlying biochemistry and the associated automation and engineering. Many of these trends preceded the emergence of the SARS-CoV-2 virus in 2019, although the pandemic certainly has hastened (and magnified) the