MAY 16, 2025

USPSTF: Updated Guidance for Syphilis Screening During Pregnancy

By Meaghan Lee Callaghan

The  U.S. Preventive Services Task Force (USPSTF) is continuing to recommend early, universal syphilis screening during pregnancy. 

The new guidance, a restatement of its 2018 guideline, comes at a time when syphilis cases remain high in the United States. That also includes congenital syphilis, which caused 279 stillbirths or neonatal/infant deaths in 2023—the highest number in 30 years.

“The USPSTF found no new substantial evidence that could change