Low doses of a highly potent, long-acting experimental antiretroviral agent were shown to suppress HIV in animals, and are likely to suppress HIV in humans as well, according to two separate studies presented at CROI 2018 in Boston.
For the animal study, all eight rhesus macaques remained uninfected after four intrarectal challenges with simian–human immunodeficiency virus (SHIV) when given the investigational drug, MK-8591 (Merck), at 1.3 and 0.43 mg/kg once weekly for six