By Landon Gray
The Plasmodium falciparum sporozoite vaccine (PfSPZ, Sanaria), a three-dose regimen of a whole-parasite vaccine against malaria, has demonstrated safety and effectiveness in adults living in Burkina Faso, West Africa, according to a recent release.
The PfSPZ vaccine is made with a live-attenuated form of P. falciparum.
Researchers assessed the safety, efficacy and immunogenicity of the three-dose regimen in two parts. The first was an open-label dose-escalation trial in 2016 that